⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butanol SCHEMBL2012224 | 0.88 | TSHR (1.00) | — | |
| Butanol SCHEMBL55899 | 0.88 | — | — | |
| Butanol SCHEMBL1418 | 0.88 | — | — | |
| Butanol SCHEMBL55049 | 0.88 | — | — | |
| Butanol SCHEMBL11279708 | 0.85 | — | — | |
| Butanol SCHEMBL8714683 | 0.85 | — | — | |
| Butanol SCHEMBL1554783 | 0.84 | — | — | |
| Butanol SCHEMBL7908046 | 0.84 | — | — | |
| Butanol SCHEMBL22118216 | 0.84 | TSHR (0.91) | — | |
| Butanol SCHEMBL5697609 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898325-B | Tigecycline crystal and preparation method thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2015-07-08 | — | — | CN | claimed |
| CN-102898325-A | Tigecycline crystal and preparation method thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-102898325-B | Tigecycline crystal and preparation method thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2015-07-08 | — | — | CN | disclosed |
| CN-102898325-A | Tigecycline crystal and preparation method thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2013-01-30 | — | — | CN | disclosed |
| US-7915423-B2 | Dissolving pantoprazole and sodium hydroxide in 2-propanol, tetrahydrofuran, acetonitrile, methanol, ethanol, water, mixtures of sec-butanol and dichloromethane, or ethyl acetate diluent, crystallizing pantoprazole sodium sesquihydrate, isolating | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2011-03-29 | — | — | US | disclosed |
| US-7507829-B2 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICALS INDUSTRIES, LTD (IL) | 2009-03-24 | — | — | US | disclosed |
| US-20080132707-A1 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICALS USA, INC. FOR BARBADOS. | 2008-06-05 | — | — | US | disclosed |
| US-20040177804-A1 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-09-16 | — | — | US | disclosed |
| EP-0495265-B1 | Acid-labile linker molecules | AKZO NOBEL NV (NL) | 1994-08-03 | — | — | EP | disclosed |
| US-5306809-A | Cancer immune therapy | AKZO N.V. (NL) | 1994-04-26 | — | — | US | disclosed |
| EP-0354819-B1 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5180712-A | Alzheimer's disease | FUJIREBIO KABUSHIKI KAISHA (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0495265-A1 | Acid-labile linker molecules | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |
| EP-0354819-A2 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| EP-0161017-B1 | PEPTIDES | AKZO N.V. (NL) | 1987-06-16 | — | — | EP | disclosed |
| US-4623640-A | Peptides | AKZO N.V. (NL) | 1986-11-18 | — | — | US | disclosed |
| EP-0161017-A1 | Peptides | AKZO N.V. (NL) | 1985-11-13 | — | — | EP | disclosed |