Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705143 | 0.98 | CYP2D6 (0.37) | CYP2D6SOS1SOS2 | |
| SCHEMBL16304065 | 0.92 | SOS1 (0.39) | CYP2D6SOS1SOS2 | |
| SCHEMBL18705147 | 0.87 | CYP2D6 (0.41) | CYP2D6SOS1SOS2 | |
| SCHEMBL15292686 | 0.86 | SOS1 (0.34) | CYP2D6SOS1SOS2 | |
| SCHEMBL18705145 | 0.83 | SOS1 (0.35) | SOS1SOS2 | |
| SCHEMBL18705148 | 0.82 | SOS1 (0.34) | SOS1SOS2 | |
| SCHEMBL17886528 | 0.81 | SOS1 (0.36) | SOS1SOS2 | |
| SCHEMBL18705146 | 0.80 | SOS1 (0.37) | CYP2D6SOS1SOS2 | |
| SCHEMBL20148749 | 0.78 | CYP2D6 (0.41) | CYP2D6 | |
| SCHEMBL21142662 | 0.77 | CYP2D6 (0.37) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065883-A1 | Triazolo [4, 5- B] Pyridin Derivatives | Centro Nacional de Investigaceiones Oncologicas (CNIO) (ES) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065883-A1 | Triazolo [4, 5- B] Pyridin Derivatives | PIM1, PIM3, PIM2 | CYP2D6 1232/4885SOS1 3907/4885SOS2 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.