SCHEMBL14768902

CC(=O)O[C@@H](C1C[C@@H](C)[C@H]2C(O1)C(=O)[C@@]1(C)C3CC[C@H]4C(C)(C)[C@@H](O[C@H]5CN(C)CCO5)CC[C@@]45C[C@@]35CC[C@]21C)C(C)(C)O

nearest known ligand 0.72

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	11/20	0.72

▸	PSEN2	P49810	11/20	0.72

▸	APH1B	Q8WW43	11/20	0.72

▸	NCSTN	Q92542	11/20	0.72

▸	APH1A	Q96BI3	11/20	0.72

▸	PSENEN	Q9NZ42	11/20	0.72

▸	APP	P05067	9/20	0.61

▸	CYP3A4	P08684	3/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14751788	1.00	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14753621	1.00	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14751858	1.00	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14750095	1.00	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14751811	1.00	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12210262	0.91	PSEN1 (0.68)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14751711	0.91	PSEN1 (0.69)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14773154	0.91	PSEN1 (0.69)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14753392	0.91	PSEN1 (0.69)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14749457	0.91	PSEN1 (0.70)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013036679-A1	COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS	SATORI PHARMACEUTICALS, INC. (US)	2013-03-14	—	—	WO	disclosed