Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.57 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768997 | 0.93 | GCK (0.51) | GCKKDR | |
| SCHEMBL1329372 | 0.88 | GCK (0.57) | GCKKDR | |
| SCHEMBL2656200 | 0.88 | GCK (0.43) | GCKKDR | |
| SCHEMBL1328943 | 0.88 | GCK (0.45) | GCKKDRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1328907 | 0.88 | GCK (0.56) | GCKKDR | |
| Hydrochloric Acid SCHEMBL1329792 | 0.88 | GCK (0.45) | GCKKDRMEN1KMT2A | |
| SCHEMBL16467545 | 0.86 | GCK (0.42) | GCKKDR | |
| SCHEMBL1330522 | 0.86 | KDR (0.43) | GCKKDR | |
| SCHEMBL1329157 | 0.85 | GCK (0.49) | GCKKDR | |
| Hydrochloric Acid SCHEMBL1328258 | 0.85 | KDR (0.42) | GCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065901-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065901-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065901-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | GCK, GCKR, GALK1 | GCK 1/4885KDR 2939/4885MEN1 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.