Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 11/20 | 0.88 |
| ▸ | PIM1 | P11309 | 9/20 | 0.76 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222293 | 0.96 | PIM2 (0.92) | PIM2PIM1PIM3 | |
| SCHEMBL2178970 | 0.94 | PIM2 (1.00) | PIM2PIM1PIM3 | |
| SCHEMBL14768480 | 0.92 | PIM2 (0.86) | PIM2PIM1PIM3 | |
| SCHEMBL14762416 | 0.92 | PIM2 (0.86) | PIM2PIM1PIM3 | |
| SCHEMBL14762135 | 0.90 | PIM1 (0.90) | PIM2PIM1PIM3 | |
| SCHEMBL2178777 | 0.86 | PIM1 (1.00) | PIM2PIM1PIM3 | |
| SCHEMBL14762211 | 0.86 | PIM2 (0.75) | PIM2PIM1PIM3 | |
| SCHEMBL2176498 | 0.84 | PIM2 (1.00) | PIM2PIM1PIM3 | |
| SCHEMBL2178598 | 0.84 | PIM2 (0.72) | PIM2PIM1PIM3 | |
| SCHEMBL2177645 | 0.84 | PIM2 (0.73) | PIM2PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (ES) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | PIM1, PIM2, PIM3 | PIM2 2/4885PIM1 1/4885PIM3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.