SCHEMBL14770844

SCHEMBL14770844

CCCC(C)(O)c1cccc(O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.42
ESR2 Q92731 4/20 0.42
KIF11 P52732 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 2/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ACHE P22303 2/20 0.39
AR P10275 1/20 0.39
TSHR P16473 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
DRD4 P21917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10638645 0.91 ESR2 (0.44) ESR1ESR2KIF11OPRM1DRD2
SCHEMBL10639109 0.90 CNR1 (0.43) ESR1ESR2KIF11OPRM1DRD2
SCHEMBL2399948 0.86 ESR1 (0.42) ESR1ESR2KIF11ALDH1A1CYP3A4
SCHEMBL13815889 0.86 ESR1 (0.42) ESR1ESR2KIF11ALDH1A1CYP3A4
SCHEMBL5648833 0.85 CNR1 (0.43) ESR1ESR2KIF11ALDH1A1CYP3A4
SCHEMBL10515022 0.79 ESR1 (0.50) ESR1ESR2KIF11ALDH1A1CYP3A4
SCHEMBL5645169 0.78 CNR1 (0.51) ESR1ESR2KIF11
SCHEMBL25571330 0.78 HIF1A (0.41) ESR1ESR2KIF11ALDH1A1CYP3A4
SCHEMBL10538090 0.78 ESR1 (0.59) ESR1ESR2KIF11AR
SCHEMBL29763582 0.78 ESR1 (0.41) ESR1ESR2KIF11ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013034567-A2 SURFACTANTS LAFARGE (FR) 2013-03-14 WO disclosed