Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503314 | 0.83 | PNP (0.56) | STING1PDE3BPDE3AUSP2PNP | |
| SCHEMBL18744083 | 0.73 | PNP (0.54) | USP2PNPTSHREDNRAHTR2A | |
| SCHEMBL97280 | 0.72 | PNP (0.53) | STING1PDE3BPDE3AUSP2PNP | |
| Acyclovir SCHEMBL40723 | 0.72 | PNP (0.67) | USP2PNPTSHREDNRAHTR2A | |
| SCHEMBL18190780 | 0.71 | PNP (0.47) | USP2PNPTSHREDNRAHTR2A | |
| Ganciclovir SCHEMBL3034 | 0.71 | BLM (0.67) | PDE3AUSP2PNPTSHREDNRA | |
| SCHEMBL13341127 | 0.70 | STING1 (0.75) | STING1PDE3BPDE3ABLM | |
| SCHEMBL29486908 | 0.70 | STING1 (0.75) | STING1PDE3BPDE3ABLM | |
| SCHEMBL4283932 | 0.70 | STING1 (0.75) | STING1PDE3BPDE3ABLM | |
| Ganciclovir SCHEMBL147839 | 0.70 | BLM (0.65) | PDE3AUSP2PNPTSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |