SCHEMBL14773097

COC(C[C@@H](C)[C@H]1C[C@H](O)[C@@]2(C)C3CC[C@H]4C(C)(C)[C@@H](O[C@H]5CN(C6CN(C(C)C)C6)CCO5)CC[C@@]45CC35CC[C@]12C)[C@H](O)C(C)(C)O

nearest known ligand 0.58

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	APP	P05067	19/20	0.58

▸	CYP3A4	P08684	11/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14751753	0.95	APP (0.52)	APPCYP3A4
SCHEMBL12234795	0.93	APP (0.53)	APPCYP3A4
SCHEMBL12234794	0.93	APP (0.53)	APPCYP3A4
SCHEMBL14773616	0.93	APP (0.58)	APPCYP3A4
SCHEMBL14755402	0.91	APP (0.55)	APPCYP3A4
SCHEMBL14755383	0.90	APP (0.55)	APPCYP3A4
SCHEMBL12233443	0.89	APP (0.46)	APPCYP3A4
SCHEMBL12232907	0.89	APP (0.55)	APPCYP3A4
SCHEMBL14753167	0.88	APP (0.48)	APPCYP3A4
SCHEMBL12233447	0.88	APP (0.48)	APPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013036665-A1	COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO	SATORI PHARMACEUTICALS, INC. (US)	2013-03-14	—	—	WO	disclosed