Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783716 | 0.81 | FNTA (0.52) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL14774702 | 0.77 | PTGER1 (0.54) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL23851495 | 0.77 | MAPK14 (0.47) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL18783649 | 0.77 | PTGER1 (0.51) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL22527755 | 0.76 | MAPK14 (0.45) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL29389988 | 0.76 | MAPK14 (0.45) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL14774660 | 0.74 | PTGER1 (0.57) | PTGER1CYP1A2CYP2C9TBXA2RPTGS1 | |
| SCHEMBL22550857 | 0.73 | CYP2C19 (0.50) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL26908042 | 0.73 | PTGER1 (0.48) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL29975031 | 0.73 | CYP2C19 (0.50) | MAPK14PTGER1CYP1A2CYP2C9TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766344-B1 | EP1 RECEPTOR LIGANDS | ESTEVE LABOR DR (ES) | 2017-05-03 | — | — | EP | disclosed |
| EP-2570125-A1 | Ep1 receptor ligands | Almirall, S.A. (ES) | 2013-03-20 | — | — | EP | disclosed |