Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962591 | 0.86 | TAAR1 (0.44) | LTA4HHTR2CSLC6A2SLC6A4TAAR1 | |
| SCHEMBL4292539 | 0.84 | TAAR1 (0.42) | LTA4HHTR2CSLC6A2SLC6A4TAAR1 | |
| SCHEMBL5562915 | 0.84 | TAAR1 (0.42) | LTA4HHTR2CSLC6A2SLC6A4TAAR1 | |
| SCHEMBL5562909 | 0.84 | TAAR1 (0.42) | LTA4HHTR2CSLC6A2SLC6A4TAAR1 | |
| SCHEMBL26881718 | 0.81 | HRH3 (0.49) | HRH3LTA4HSLC6A2SLC6A4PARP1 | |
| SCHEMBL5504868 | 0.81 | HRH3 (0.49) | HRH3LTA4HSLC6A2SLC6A4PARP1 | |
| SCHEMBL10132546 | 0.79 | POLB (0.56) | LTA4HHTR2C | |
| SCHEMBL22456442 | 0.79 | POLB (0.56) | LTA4HHTR2C | |
| SCHEMBL4749981 | 0.78 | HRH3 (0.49) | HRH3LTA4HL3MBTL1PARP1 | |
| SCHEMBL5563370 | 0.78 | HRH3 (0.49) | HRH3LTA4HHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| CN-1152877-C | Piperazine derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1334812-A | Piperazine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-02-06 | — | — | CN | disclosed |