Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010804 | 0.91 | KCNH2 (0.55) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010799 | 0.91 | KCNH2 (0.55) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010920 | 0.91 | KCNH2 (0.46) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| Hydrochloric Acid SCHEMBL14774897 | 0.90 | KCNH2 (0.47) | KCNH2CACNA1CSCN5AMAPK1PTGS1 | |
| SCHEMBL14775037 | 0.90 | KCNH2 (0.45) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010642 | 0.88 | KCNH2 (0.46) | KCNH2CACNA1CSCN5AKDM4EPTGS1 | |
| SCHEMBL6010648 | 0.88 | KCNH2 (0.46) | KCNH2CACNA1CSCN5AKDM4EPTGS1 | |
| SCHEMBL6010969 | 0.86 | KCNH2 (0.59) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010973 | 0.86 | KCNH2 (0.59) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL14774954 | 0.86 | KCNH2 (0.43) | KCNH2CACNA1CSCN5APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |