Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229247 | 0.82 | CHRM1 (0.42) | CHRM1MITFGRM2KCNH2ALDH1A1 | |
| SCHEMBL5541985 | 0.80 | CHRM1 (0.40) | CHRM1MITFGRM2KCNH2ALDH1A1 | |
| SCHEMBL5539431 | 0.80 | CHRM1 (0.44) | CHRM1MITFGRM2KCNH2ALDH1A1 | |
| SCHEMBL5539172 | 0.79 | CHRM1 (0.39) | CHRM1MITFGRM2KCNH2ALDH1A1 | |
| SCHEMBL18031624 | 0.78 | CHRM1 (0.41) | CHRM1MITFGRM2KCNH2ALDH1A1 | |
| SCHEMBL1227391 | 0.78 | CHRM1 (0.40) | CHRM1GRM2KCNH2ALDH1A1 | |
| SCHEMBL5537422 | 0.77 | CHRM1 (0.37) | CHRM1MITFKCNH2ALDH1A1 | |
| SCHEMBL12901278 | 0.76 | GRM2 (0.47) | CHRM1GRM2KCNH2 | |
| SCHEMBL3466318 | 0.74 | GRM2 (0.46) | CHRM1GRM2KCNH2LMNAALDH1A1 | |
| SCHEMBL5538961 | 0.74 | CHRM1 (0.35) | CHRM1KCNH2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |