SCHEMBL1477546

SCHEMBL1477546

COc1cc(O)cc2cc(O)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
ESR1 P03372 6/20 0.53
ESR2 Q92731 5/20 0.53
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
FTO Q9C0B1 1/20 0.42
APP P05067 1/20 0.41
KDM5A P29375 1/20 0.41
MAOA P21397 1/20 0.40
PTPN1 P18031 1/20 0.40
FLT3 P36888 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477716 0.86 ESR1 (0.56) MAOBESR1ESR2CYP3A4MAPT
SCHEMBL7551728 0.82 NQO2 (0.55) MAOBESR1ESR2CYP3A4MAPT
Flavanthrinin SCHEMBL30544847 0.81 ESR1 (0.51) MAOBESR1ESR2CYP3A4MAPT
Flavanthrinin SCHEMBL30544846 0.81 ESR1 (0.51) MAOBESR1ESR2CYP3A4MAPT
Flavanthrinin SCHEMBL29054933 0.81 ESR1 (0.51) MAOBESR1ESR2CYP3A4MAPT
SCHEMBL10702559 0.81 HTT (0.56) PTGS2PTPN1
SCHEMBL3163561 0.80 KDM4E (0.51) MAOBESR1ESR2CYP3A4MAPT
SCHEMBL30203238 0.80 KDM4E (0.51) MAOBESR1ESR2CYP3A4MAPT
Resorcinol SCHEMBL10357607 0.80 ESR1 (0.50) MAOBESR1ESR2CYP3A4MAPT
Flavanthrinin SCHEMBL29054952 0.80 ESR1 (0.50) MAOBESR1ESR2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5151458-A Molding materials for liquid crystal resins BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US claimed
US-5143956-A Blends with low molecular weight liquid crystals BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
US-5102935-A With low molecular weight, liquid crystalline esters and/or ester amides BAYER AKTIENGESELLSCHAFT (DE) 1992-04-07 US claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
EP-1991286-B1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENT LTD (BB) 2012-12-26 EP disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20110092999-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-21 US disclosed
US-7914485-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-29 US disclosed
EP-0141320-B1 THERMOTROPIC AROMATIC POLYESTERS WITH HIGH STIFFNESS, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND FILMS BAYER AG (DE) 1987-10-07 EP disclosed
EP-0232777-A2 Method of manufacturing parts of thermotropic liquid crystalline plastics with a defined orientation of the liquid crystal polymer molecule, and the parts so produced BAYER AG (DE) 1987-08-19 EP disclosed
US-4599395-A Thermotropic, aromatic polyesters having good mechanical strength, containing sulfonic acid groups or metal sulfonate groups a process for the production thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0024499-B1 BIAXIALLY ORIENTED WHOLLY AROMATIC POLYESTER FILM AND PROCESS FOR PRODUCING SAME TEIJIN LIMITED (JP) 1984-03-07 EP disclosed
US-4333907-A Biaxially oriented wholly aromatic polyester film TEITIN LIMITED (JP) 1982-06-08 US disclosed
EP-0024499-A1 Biaxially oriented wholly aromatic polyester film and process for producing same TEIJIN LIMITED (JP) 1981-03-11 EP disclosed