Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852851 | 0.89 | PDE7A (0.70) | PDE7A | |
| SCHEMBL852702 | 0.87 | PDE7A (0.72) | PDE7A | |
| SCHEMBL880663 | 0.87 | PDE7A (0.75) | PDE7A | |
| SCHEMBL853175 | 0.86 | PDE7A (0.68) | PDE7A | |
| SCHEMBL853013 | 0.86 | PDE7A (0.71) | PDE7A | |
| SCHEMBL853249 | 0.86 | PDE7A (0.71) | PDE7A | |
| SCHEMBL852714 | 0.85 | PDE7A (0.67) | PDE7A | |
| SCHEMBL855150 | 0.85 | PDE7A (0.68) | PDE7A | |
| Hydrochloric Acid SCHEMBL853804 | 0.85 | PDE7A (0.70) | PDE7A | |
| SCHEMBL861451 | 0.85 | PDE7A (0.70) | PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1775298-B1 | THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY | DAIICHI SANKYO CO LTD (JP) | 2013-03-20 | — | — | EP | claimed |