SCHEMBL14775680

SCHEMBL14775680

CCOC(=O)CCCCCCN1C(=O)CC[C@H]1C=C[C@H](O)Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 14/20 0.79
PTGER3 P43115 5/20 0.79
PTGER2 P43116 4/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685698 1.00 PTGER4 (0.79) PTGER4PTGER3PTGER2
SCHEMBL4990794 0.89 PTGER4 (0.63) PTGER4PTGER3PTGER2
SCHEMBL6165091 0.88 PTGER4 (1.00) PTGER4PTGER3PTGER2
SCHEMBL6165089 0.88 PTGER4 (1.00) PTGER4PTGER3PTGER2
SCHEMBL10210123 0.88 PTGER4 (1.00) PTGER4PTGER3PTGER2
SCHEMBL6714298 0.88 PTGER4 (0.65) PTGER4PTGER3PTGER2
SCHEMBL4994256 0.88 PTGER4 (0.65) PTGER4PTGER3PTGER2
SCHEMBL14775818 0.87 PTGER4 (0.77) PTGER4PTGER3PTGER2
SCHEMBL10210081 0.87 PTGER4 (0.81) PTGER4PTGER3PTGER2
SCHEMBL4987207 0.87 PTGER4 (0.81) PTGER4PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503984-B1 8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE ALLERGAN INC (US) 2013-03-20 EP claimed