Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775941 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL2686028 | 0.93 | HDAC1 (0.68) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775832 | 0.91 | HDAC1 (0.65) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL2684783 | 0.91 | HDAC1 (0.65) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL2686562 | 0.91 | HDAC1 (0.68) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2688225 | 0.91 | HDAC1 (0.73) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2684918 | 0.90 | HDAC1 (0.66) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL2686054 | 0.90 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2686529 | 0.89 | HDAC1 (0.61) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL2687174 | 0.89 | HDAC1 (0.61) | HDAC1HDAC2HDAC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991226-B1 | INHIBITORS OF HISTONE DEACETYLASE | MERCK SHARP & DOHME (US) | 2013-03-20 | — | — | EP | claimed |