Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.70 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.56 |
| ▸ | PDE8A | O60658 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100679 | 0.91 | PDE7A (0.86) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL30837853 | 0.91 | PDE7A (0.86) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL99715 | 0.89 | PDE7A (0.80) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL99954 | 0.86 | PDE7A (0.75) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL100608 | 0.83 | PDE7A (1.00) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL30837886 | 0.83 | PDE7A (1.00) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL173167 | 0.82 | PDE7A (0.78) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL581953 | 0.82 | PDE7A (0.78) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL32681324 | 0.82 | PDE7A (0.78) | PDE7APDE7BPDE8AMEN1KMT2A | |
| SCHEMBL100673 | 0.82 | PDE7A (0.91) | PDE7APDE7BPDE8AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411009-B1 | Therapeutic uses of quinazolinedione derivatives | SANOFI SA (FR) | 2013-03-20 | — | — | EP | claimed |