Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256781 | 0.89 | KCNH2 (0.48) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| Trifluoroacetic Acid SCHEMBL5536133 | 0.84 | KCNH2 (0.56) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| Trifluoroacetic Acid SCHEMBL5536139 | 0.83 | KCNH2 (0.52) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| Trifluoroacetic Acid SCHEMBL5542817 | 0.81 | KCNH2 (0.57) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| Trifluoroacetic Acid SCHEMBL5536449 | 0.78 | KCNH2 (0.44) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL29256782 | 0.77 | KCNH2 (0.50) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL5542823 | 0.74 | KCNH2 (0.56) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL13461164 | 0.74 | KCNH2 (0.52) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL5544194 | 0.73 | KCNH2 (0.53) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL13113855 | 0.73 | KCNH2 (0.51) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |