Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14777401 | 0.86 | SGK1 (0.75) | SGK1 | |
| SCHEMBL14775263 | 0.84 | SGK1 (0.76) | SGK1 | |
| SCHEMBL14812724 | 0.83 | SGK1 (0.71) | SGK1 | |
| SCHEMBL14775002 | 0.77 | SGK1 (0.76) | SGK1CYP3A4 | |
| SCHEMBL16053090 | 0.77 | SGK1 (0.86) | SGK1 | |
| SCHEMBL16053152 | 0.77 | SGK1 (1.00) | SGK1 | |
| SCHEMBL17022836 | 0.75 | SGK1 (0.64) | SGK1CYP3A4 | |
| SCHEMBL14775097 | 0.73 | SGK1 (0.76) | SGK1CYP3A4 | |
| SCHEMBL14774971 | 0.73 | SGK1 (0.61) | SGK1CYP3A4 | |
| SCHEMBL14775006 | 0.73 | SGK1 (0.77) | SGK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072493-A1 | N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-03-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072493-A1 | N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS | SGK1, SGK3, SGK2 | SGK1 1/4885CYP3A4 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.