Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172559 | 0.88 | SLC7A5 (0.55) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL8306982 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL4249865 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL28318850 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL4242294 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL4242870 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL15390388 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL4249863 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| SCHEMBL11559690 | 0.80 | SLC7A5 (0.47) | HSD17B10USP2PKMALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL30461880 | 0.79 | SLC7A5 (0.46) | HSD17B10USP2PKMALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586988-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-8557781-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-8399614-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-03-19 | — | — | US | disclosed |