⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932406 | 0.74 | — | — | |
| SCHEMBL1932405 | 0.74 | — | — | |
| SCHEMBL4952624 | 0.70 | — | — | |
| SCHEMBL5797965 | 0.70 | — | — | |
| SCHEMBL3579406 | 0.59 | — | — | |
| SCHEMBL269291 | 0.59 | — | — | |
| SCHEMBL12131287 | 0.56 | — | — | |
| SCHEMBL12304870 | 0.56 | — | — | |
| SCHEMBL168821 | 0.56 | — | — | |
| SCHEMBL168820 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077418-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | CHEMINOVA A/S (DK) | 2011-03-31 | — | — | US | disclosed |
| WO-2010094164-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | CHEMINOVA A/S (DK) | 2010-08-26 | — | — | WO | disclosed |
| US-20090036713-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | EVONIK DEGUSSA GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
| EP-1991520-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | Evonik Degussa GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007101769-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | EVONIK DEGUSSA GMBH (DE) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213540-A1 | Process for the hydrogenation of imines | DEGUSSA AG (DE) | 2007-09-13 | — | — | US | disclosed |
| US-6822118-B1 | CATALYTIC REACTION USING IRIDIUM COMPOUND UNDER HIGH PRESSURE IN PRESENCE OF METAL- OR AMMONIUM- CHLORIDE, BROMIDE, OR IODIDE AND ACID | SYNGENTA CROP PROTECTION, INC. | 2004-11-23 | — | — | US | disclosed |
| EP-0850241-B1 | IRIDIUM-DIPHOSPHINE COMPLEXES AND PROCESS FOR THE HYDROGENATION OF IMINES | NOVARTIS AG (CH) | 2001-08-29 | — | — | EP | disclosed |
| US-6218559-B1 | REACTION PRODUCTS OF AN IRIDIUM(III) SALT OR A HYDRATE THEREOF, A DIPHOSPHINE HAVING SECONDARY PHOSPHINE GROUPS AND A METAL OR AMMONIUM CHLORIDE, BROMIDE OR IODIDE | NOVARITIS CORPORATION | 2001-04-17 | — | — | US | disclosed |
| EP-0848697-B1 | PROCESS FOR THE HYDROGENATION OF IMINES | NOVARTIS AG (CH) | 2000-10-04 | — | — | EP | disclosed |
| EP-0301457-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE SECONDARY AMINES | CIBA-GEIGY AG (CH) | 1993-09-29 | — | — | EP | disclosed |
| US-5112999-A | With diphosphines and diphosphinites, catalysts for hydrogenation of imines to secondary amines | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0256982-B1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE SECONDARY ARYL AMINES | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-5011995-A | Hydrogenation of N-Aliphatic Keimines Using A Complex Iridium Catalyst | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0419409-A2 | Iridium complexes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |
| US-4996361-A | Catalytic hydrogenation of ketimine | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1991-02-26 | — | — | US | disclosed |
| US-4994615-A | Hydrogenation of prochiral N-arylketimines using iridium catalyst | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0302021-A2 | Process for the preparation of optically active secondary aryl amines | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1989-02-01 | — | — | EP | disclosed |
| EP-0301457-A2 | Process for the preparation of optically active secondary amines | CIBA-GEIGY AG (CH) | 1989-02-01 | — | — | EP | disclosed |
| EP-0256982-A2 | Method for the preparation of optically active secondary aryl amines | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |