Prochloraz

Prochloraz

SCHEMBL1478635

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1.ClCCl

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.96
ADRB2 P07550 5/20 0.40
ADRB1 P08588 5/20 0.40
ADRB3 P13945 5/20 0.40
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL22242 0.98 AHR (1.00) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL34675 0.98 AHR (1.00) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL12611119 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL5454581 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL7128363 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL11376171 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL9371936 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL11375792 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL11379280 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL10346525 0.97 AHR (0.98) AHRADRB2ADRB1ADRB3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108169380-A A kind of deriving method for high performance liquid chromatography detection perfluoro caprylic acid 浙江工业大学 2018-06-15 CN claimed
CN-108129541-A A kind of triterpene compound and its methods and applications extracted from ganoderma lucidum 成都普思生物科技股份有限公司 2018-06-08 CN claimed
CN-107406440-B BACE1 inhibitors 豪夫迈·罗氏有限公司 2021-05-07 CN disclosed
CN-110205821-A A kind of green free-floride water-proof aagent and its application in fibre 广州百思创科技有限公司 2019-09-06 CN disclosed
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-108129541-A A kind of triterpene compound and its methods and applications extracted from ganoderma lucidum 成都普思生物科技股份有限公司 2018-06-08 CN disclosed
CN-107840842-A Alkynes is for heterocyclic compound, its preparation method and its in application pharmaceutically 北京天诚医药科技有限公司 2018-03-27 CN disclosed
CN-107698593-A Heterocyclic compound as FGFR inhibitor 南京天印健华医药科技有限公司 2018-02-16 CN disclosed
CN-107619388-A Heterocyclic compound as FGFR inhibitor 南京天印健华医药科技有限公司 2018-01-23 CN disclosed
CN-107428747-A Substituted pyridobenzodiazepine ketone derivative and use thereof 拜耳制药股份公司 2017-12-01 CN disclosed
EP-3246027-A1 INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER GlaxoSmithKline LLC (US) 2017-11-22 EP disclosed
CN-100581545-C Siromosi medicinal composition and its making method FUJIAN MICROBIAL INST 2010-01-20 CN disclosed
CN-101090714-A Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation ACTELION PHARMACEUTICALS LTD (US) 2007-12-19 CN disclosed
CN-1939302-A Siromosi medicinal composition and its making method FUJIAN MICROBIAL INST (CN) 2007-04-04 CN disclosed
CN-1278681-C Adduct of topiramate and tramadol hydrochloride and uses thereof CILAG AG (CH) 2006-10-11 CN disclosed
EP-1507758-B1 INDOLE DERIVATIVES AND THEIR USE AS LIGANDS FOR CB2 RECEPTORS SANOFI AVENTIS (FR) 2005-11-02 EP disclosed
CN-1652767-A Adduct of topiramate and tramadol hydrochloride and its use CILAG AG (CH) 2005-08-10 CN disclosed
EP-1060178-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES PFIZER (US) 2003-09-03 EP disclosed
CN-1239889-A Novel compounds useful as neuroprotective agents LILLY CO ELI (US) 1999-12-29 CN disclosed
CN-87103510-A Substituted pyridine herbicide 1988-01-20 CN disclosed