Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL19919 | 0.95 | — | — | |
| Acetic Acid SCHEMBL4818925 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL7611510 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL80426 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL6266605 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25236528 | 0.90 | CA1 (0.90) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL527559 | 0.90 | — | — | |
| Acetic Acid SCHEMBL10816445 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL7060080 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL9542974 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116124747-A | Colorimetric card for rapidly detecting concentration of hesperidin and manufacturing method and application thereof | 韩山师范学院 | 2023-05-16 | — | — | CN | claimed |
| CN-111442961-A | Method for analyzing distribution and transportation route of xanthone compounds in pummelo peel | 广东石油化工学院 | 2020-07-24 | — | — | CN | claimed |
| CN-107807100-A | A kind of method for building up and purification process of madder medicinal material Radix Rubiae total anthraquinones assay | 广州中医药大学 | 2018-03-16 | — | — | CN | claimed |
| CN-106946830-A | The extraction separation of flavone compound and Histochemical localization method in seven color bamboo stalks | 西南林业大学 | 2017-07-14 | — | — | CN | claimed |
| CN-106706626-A | Ingredient identification and antibacterial activity evaluation method of cliff honeysuckle | 西南民族大学 | 2017-05-24 | — | — | CN | claimed |
| CN-104324090-A | Rhubarb total anthraquinone capsule composition | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2015-02-04 | — | — | CN | claimed |
| CN-104324089-A | Rhubarb total anthraquinone being stable and uniform in proportion of various components and composition thereof used in jaundice-eliminating treatment of viral hepatitis type B | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2015-02-04 | — | — | CN | claimed |
| CN-104288243-A | Total anthraquinone and compositions thereof for resisting rheumatism | JIANGXI BAISHEN PHARMACEUTICAL CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-104288242-A | Total anthraquinone and compositions thereof treating Parkinson's disease | JIANGXI BAISHEN PHARMACEUTICAL CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-104257768-A | Application of total anthraquinone with various ingredients in stable and uniform proportion and composition of total anthraquinone to treatment of pancreatitis | JIANGXI BAISHEN PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-104257769-A | Rheum officinale total anthraquinones with ingredients in stable and uniform proportions and composition of rheum officinale total anthraquinones for resisting hepatitis B virus | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-104224952-A | Preparation method for total anthraquinones of rheum officinale with stable and uniform proportions of all components | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-104224951-A | Total anthraquinones with stable and uniform proportions of various components and composition of total anthraquinones for treating cholecystitis | JIANGXI BAISHEN PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-104224953-A | Total anthraquinones with stable and uniform proportions of various components and composition of total anthraquinones for treating chronic renal failure | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-103319322-A | Method, using response surface methodology, for optimizing ultrasonic extraction technology of free anthraquinone from cassia seeds | BOZHOU SHENGLIN CHINESE HERBAL MEDICINE PIECES CO LTD | 2013-09-25 | — | — | CN | claimed |
| CN-103091445-A | Quality detection method of Eleutherine plicata Herb and extract thereof | GUANGZHOU BAIYUN HUANAN BIO TECH CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-102038786-A | Preparation method of morinda officinalis traditional Chinese medicine | ANHUI HUQIAO TCM TECHNOLOGY CO LTD | 2011-05-04 | — | — | CN | claimed |
| CN-101451957-A | Method for detecting anthraquinone content in medicaments | SHANGHAI HUTCHISON PHARMACEUTI (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-101327247-A | Senna formulation and quality control method | HE WENJIAN (CN) | 2008-12-24 | — | — | CN | claimed |
| CN-101205176-A | Optimum process for extracting anthraquinone components from rhubarb horsetails by cell ultrasonication | UNIV HENAN AGRICULTURAL (CN) | 2008-06-25 | — | — | CN | claimed |