Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 18/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785044 | 0.92 | KCNK3 (0.83) | KCNK3 | |
| SCHEMBL14784727 | 0.90 | KCNK3 (0.69) | KCNK3GRIN1GRIN2B | |
| SCHEMBL14786414 | 0.83 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL14784992 | 0.82 | KCNK3 (0.80) | KCNK3 | |
| SCHEMBL14785369 | 0.80 | KCNK3 (0.83) | KCNK3 | |
| SCHEMBL10805998 | 0.80 | KCNK3 (0.81) | KCNK3 | |
| SCHEMBL14784582 | 0.78 | KCNK3 (0.78) | KCNK3 | |
| SCHEMBL14784171 | 0.77 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL14791430 | 0.76 | KCNK3 (1.00) | KCNK3 | |
| SCHEMBL17548581 | 0.75 | KCNK3 (0.70) | KCNK3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013037914-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINES, THEIR USE AS MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | SANOFI (FR) | 2013-03-21 | — | — | WO | disclosed |