Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 0.83 |
| ▸ | PDGFRB | P09619 | 16/20 | 0.83 |
| ▸ | KDR | P35968 | 16/20 | 0.83 |
| ▸ | FLT1 | P17948 | 3/20 | 0.62 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795312 | 0.91 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14796286 | 0.89 | FGFR1 (0.82) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14796233 | 0.87 | FGFR1 (0.76) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14795616 | 0.87 | FGFR1 (0.81) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14796203 | 0.85 | FGFR1 (0.78) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14795656 | 0.85 | FGFR1 (0.78) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14795406 | 0.85 | FGFR1 (0.78) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14795481 | 0.84 | FGFR1 (0.78) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL15911012 | 0.84 | FGFR1 (0.84) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL14795941 | 0.84 | FGFR1 (0.71) | FGFR1PDGFRBKDRFLT1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762475-A1 | Pharmaceutically acceptable salts of quinolinone compounds and their medical use | Novartis Vaccines and Diagnostics, Inc. (US) | 2014-08-06 | — | — | EP | disclosed |
| EP-2573079-A2 | Benzimidazole quinolinones and uses thereof | Novartis Vaccines and Diagnostics, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |