Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706578 | 0.74 | DDB1 (0.34) | CA1CA2 | |
| SCHEMBL707400 | 0.68 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL707705 | 0.68 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL2892352 | 0.65 | POLB (0.32) | CA1CA2 | |
| SCHEMBL706703 | 0.62 | TSHR (0.38) | CA1CA2 | |
| SCHEMBL3477146 | 0.56 | KDM1A (0.34) | — | |
| SCHEMBL4983556 | 0.56 | KDM1A (0.34) | — | |
| SCHEMBL12499379 | 0.55 | HDAC4 (0.44) | CA1CA2 | |
| SCHEMBL10744100 | 0.55 | KMT2A (0.41) | — | |
| SCHEMBL2572574 | 0.53 | ELANE (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144503-B9 | 4-(octahydro-2H-isoindol-2-yl)-1,3-oxazol-4-one as TACHYKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2144503-B1 | 4-(octahydro-2H-isoindol-2-yl)-1,3-oxazol-4-one as TACHYKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2013-03-27 | — | — | EP | disclosed |