SCHEMBL14797136

SCHEMBL14797136

Cc1ccccc1Oc1ncc2nc(-c3cc(C)c(OCC(=O)O)c(C)c3)oc2n1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.71
CETP P11597 11/20 0.41
CEPT1 Q9Y6K0 9/20 0.39
MAPT P10636 3/20 0.39
RXFP1 Q9HBX9 1/20 0.39
TP53 P04637 2/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2225216 0.93 S1PR1 (0.69) S1PR1CETPCEPT1MAPTRXFP1
SCHEMBL14797016 0.92 S1PR1 (0.73) S1PR1CETPCEPT1MAPTTHRB
SCHEMBL2223368 0.90 S1PR1 (0.83) S1PR1CETPMAPT
SCHEMBL14797014 0.90 S1PR1 (0.68) S1PR1CETPMAPTRXFP1TP53
SCHEMBL14797212 0.90 S1PR1 (0.66) S1PR1CETPCEPT1MAPTRXFP1
SCHEMBL14797002 0.89 S1PR1 (0.65) S1PR1CETPCEPT1THRB
SCHEMBL14797108 0.89 S1PR1 (0.70) S1PR1CEPT1MAPTRXFP1TP53
SCHEMBL14797000 0.88 S1PR1 (0.74) S1PR1CETPCEPT1MAPTTP53
SCHEMBL14797341 0.88 S1PR1 (0.76) S1PR1CETPCEPT1MAPTRXFP1
SCHEMBL14796982 0.87 S1PR1 (0.67) S1PR1CETPCEPT1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846692-B2 Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring SANOFI (FR) 2014-09-30 US disclosed
US-20130079358-A1 CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING SANOFI (FR) 2013-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130079358-A1 CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING OXGR1, EDNRA, EDF1 S1PR1 129/4885CETP 3150/4885CEPT1 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.