SCHEMBL14799454

SCHEMBL14799454

CN(C)N=C1C(=NN(C)C)C(Cl)=C(Cl)C(Cl)=C1Cl

nearest known ligand 0.88

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DEPTOR Q8TB45 3/20 0.88
DUSP3 P51452 1/20 0.40
PTPN11 Q06124 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21327664 0.93 DEPTOR (1.00) DEPTORDUSP3PTPN11
SCHEMBL15438738 0.81 DEPTOR (0.67) DEPTORDUSP3PTPN11
SCHEMBL14800287 0.59 DEPTOR (0.42) DEPTOR
SCHEMBL21327594 0.57 DEPTOR (1.00) DEPTORDUSP3PTPN11
SCHEMBL21327553 0.57 DEPTOR (0.44) DEPTORDUSP3PTPN11
SCHEMBL14799501 0.55 DEPTOR (0.38) DEPTOR
SCHEMBL13278640 0.46
SCHEMBL13278651 0.46
SCHEMBL181649 0.46
SCHEMBL19288029 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed