Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminolevulinic Acid SCHEMBL16897694 | 0.88 | GABRR1 (0.47) | STAT3STAT1ALDH1A1MAPT | |
| Aminolevulinic Acid SCHEMBL4023972 | 0.88 | GABRR1 (0.47) | STAT3STAT1ALDH1A1MAPT | |
| Malonic Acid SCHEMBL27560828 | 0.87 | STAT3 (0.36) | STAT3STAT1ALDH1A1MAPT | |
| Malonic Acid SCHEMBL5133240 | 0.87 | STAT3 (0.36) | STAT3STAT1ALDH1A1MAPT | |
| Carbamic Acid SCHEMBL30568294 | 0.87 | STAT3 (0.38) | STAT3STAT1 | |
| Propionic Acid SCHEMBL27439210 | 0.86 | FFAR3 (0.36) | STAT3STAT1 | |
| Propionic Acid SCHEMBL2502176 | 0.86 | FFAR3 (0.36) | STAT3STAT1 | |
| Hydrogen Peroxide SCHEMBL28310892 | 0.84 | STAT3 (0.43) | STAT3STAT1 | |
| Propionic Acid SCHEMBL27367545 | 0.84 | STAT3 (0.35) | STAT3STAT1 | |
| SCHEMBL28643450 | 0.83 | STAT3 (0.38) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837611-B2 | Photo-switchable fullerene-based materials as interfacial layers in organic photovoltaics | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-05 | — | — | US | disclosed |
| US-20130074920-A1 | Photo-Switchable Fullerene-Based Materials as Interfacial Layers in Organic Photovoltaics | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-03-28 | — | — | US | disclosed |