Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL28119117 | 0.77 | TSHR (0.73) | TSHRMAOATDP1CYP3A4TAAR1 | |
| Aniline SCHEMBL28480918 | 0.76 | TSHR (0.55) | TSHRMAOATDP1CYP3A4TAAR1 | |
| Aniline SCHEMBL10614149 | 0.74 | TSHR (0.41) | TSHRMAOATDP1CYP3A4TAAR1 | |
| Aniline SCHEMBL14801555 | 0.72 | TSHR (0.39) | TSHRMAOATDP1CYP3A4TAAR1 | |
| Aniline SCHEMBL28303012 | 0.72 | TSHR (0.65) | TSHRMAOATDP1CYP3A4TAAR1 | |
| Aniline SCHEMBL11818606 | 0.71 | — | — | |
| Methylamine SCHEMBL16192060 | 0.71 | — | — | |
| Aniline SCHEMBL1984004 | 0.71 | — | — | |
| Aniline SCHEMBL9755597 | 0.71 | TSHR (1.00) | TSHRMAOATDP1CYP3A4TAAR1 | |
| SCHEMBL18517570 | 0.71 | TSHR (1.00) | TSHRMAOATDP1CYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351656-B2 | Silylated polyurethanes | HUNTSMAN INTERNATIONAL LLC (US) | 2019-07-16 | — | — | US | claimed |
| EP-3157970-B1 | SILYLATED POLYURETHANES | HUNTSMAN INT LLC (US) | 2019-02-06 | — | — | EP | claimed |
| US-20170198084-A1 | SILYLATED POLYURETHANES | HUNTSMAN INTERNATIONAL LLC | 2017-07-13 | — | — | US | claimed |
| EP-2957582-A1 | Isocyanate-based prepolymers | HUNTSMAN INTERNATIONAL LLC (US) | 2015-12-23 | — | — | EP | claimed |
| US-20220220247-A1 | Composition Comprising Silylated Polymer | HUNTSMAN INTERNATIONAL LLC | 2022-07-14 | — | — | US | disclosed |
| CN-113966360-A | Compositions comprising silylated polymers | 亨茨曼国际有限公司 | 2022-01-21 | — | — | CN | disclosed |
| US-10351656-B2 | Silylated polyurethanes | HUNTSMAN INTERNATIONAL LLC (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3157970-B1 | SILYLATED POLYURETHANES | HUNTSMAN INT LLC (US) | 2019-02-06 | — | — | EP | disclosed |
| EP-2989155-B1 | COMPOSITION COMPRISING SILYLATED POLYMERS | HUNTSMAN INT LLC (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9752013-B2 | Composition comprising silylated polymers | HUNTSMAN INTERNATIONAL LLC (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160046793-A1 | Composition Comprising Silylated Polymers | HUNTSMAN INTERNATIONAL LLC | 2016-02-18 | — | — | US | disclosed |
| CN-105308109-A | Composition comprising silylated polymers | HUNTSMAN INT LLC | 2016-02-03 | — | — | CN | disclosed |
| EP-2957582-A1 | Isocyanate-based prepolymers | HUNTSMAN INTERNATIONAL LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2796493-A1 | Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane | HUNTSMAN INTERNATIONAL LLC (US) | 2014-10-29 | — | — | EP | disclosed |
| US-20130079538-A1 | ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS | Huntsman Internatioanl LLC (US) | 2013-03-28 | — | — | US | disclosed |