SCHEMBL1480333

SCHEMBL1480333

CCCCCC=CCC=CCC(O)C=CC=CCCCC(=O)O

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 3/20 0.95
LTB4R2 Q9NPC1 2/20 0.74
MAPT P10636 2/20 0.74
ALDH1A1 P00352 2/20 0.74
ALOX5 P09917 1/20 0.74
LTB4R Q15722 1/20 0.74
FAAH O00519 3/20 0.69
PPARG P37231 3/20 0.68
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
USP2 O75604 1/20 0.68
LMNA P02545 1/20 0.68
TP53 P04637 1/20 0.68
CYP3A4 P08684 1/20 0.68
HSPD1 P10809 1/20 0.68
CYP19A1 P11511 1/20 0.68
FABP4 P15090 1/20 0.68
HPGD P15428 1/20 0.68
ALOX15 P16050 1/20 0.68
CASP1 P29466 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718113 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL29926444 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL8728913 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL1479341 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL7718095 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL29926968 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL29926582 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL1480331 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL1479340 1.00 OXER1 (0.95) OXER1LTB4R2MAPTALDH1A1ALOX5
SCHEMBL16670813 0.97 OXER1 (1.00) OXER1LTB4R2MAPTALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239889-A1 In vivo release of endogenous anti-microbial mediators by leukotriene B4 (LTB4) administration GOSSELIN JEAN 2005-10-27 US claimed
US-20040132820-A1 Agents with leukotriene B4-like antiviral (DNA) and anti-neoplastic activities GOSSELIN JEAN (CA) 2004-07-08 US claimed
US-6093741-A ANTI-NEOPLASTIC AGENT IN THE PROPHYLAXIS AND TREATMENT OF CANCERS INDUCED BY TUMOR VIRUSES AND IN OTHER NEOPLASIC DISEASES VIROCELL INC. (CA) 2000-07-25 US claimed
JP-2000505435-A 2000-05-09 JP claimed
EP-0881900-A1 USE OF LEUKOTRIENE B 4? OR ITS ANALOGUES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS Virocell Inc. (CA) 1998-12-09 EP claimed
WO-1997029751-A1 USE OF LEUKOTRIENE B4 OR ITS ANALOGUES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS VIROCELL INC. (CA) 1997-08-21 WO claimed
US-9612242-B2 Combined F2-isoprostane and myleoperoxidase detection, a risk indicator for cardiovascular disease THE CLEVELAND CLINIC FOUNDATION (US) 2017-04-04 US disclosed
US-9581597-B2 Myeloperoxidase, a risk indicator for cardiovascular disease THE CLEVELAND CLINIC FOUNDATION (US) 2017-02-28 US disclosed
US-9575065-B2 Myeloperoxidase, a risk indicator for cardiovascular disease THE CLEVELAND CLINIC FOUNDATION (US) 2017-02-21 US disclosed
US-9435808-B2 Myeloperoxidase, a risk indicator for cardiovascular disease THE CLEVELAND CLINIC FOUNDATION (US) 2016-09-06 US disclosed
US-20160238603-A1 MYELOPEROXIDASE, A RISK INDICATOR FOR CARDIOVASCULAR DISEASE CLEVELAND CLINIC FOUND (US) 2016-08-18 US disclosed
US-20160238605-A1 MYELOPEROXIDASE, A RISK INDICATOR FOR CARDIOVASCULAR DISEASE CLEVELAND CLINIC FOUND (US) 2016-08-18 US disclosed
US-20160238604-A1 MYELOPEROXIDASE, A RISK INDICATOR FOR CARDIOVASCULAR DISEASE CLEVELAND CLINIC FOUND (US) 2016-08-18 US disclosed
US-20040132820-A1 Agents with leukotriene B4-like antiviral (DNA) and anti-neoplastic activities GOSSELIN JEAN (CA) 2004-07-08 US disclosed
US-20030180218-A1 Systemic marker for monitoring anti-inflammatory and antioxidant actions of therapeutic agents THE CLEVELAND CLINIC FOUNDATION 2003-09-25 US disclosed
US-20020164662-A1 Myeloperoxidase, a risk indicator for cardiovascular disease NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-11-07 US disclosed
US-6093741-A ANTI-NEOPLASTIC AGENT IN THE PROPHYLAXIS AND TREATMENT OF CANCERS INDUCED BY TUMOR VIRUSES AND IN OTHER NEOPLASIC DISEASES VIROCELL INC. (CA) 2000-07-25 US disclosed
EP-0881900-A1 USE OF LEUKOTRIENE B 4? OR ITS ANALOGUES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS Virocell Inc. (CA) 1998-12-09 EP disclosed
US-5789441-A Leukotriene B4 as an antiviral and anti-neoplastic agent VIROCELL INC. (CA) 1998-08-04 US disclosed
WO-1997029751-A1 USE OF LEUKOTRIENE B4 OR ITS ANALOGUES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS VIROCELL INC. (CA) 1997-08-21 WO disclosed