⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19312410 | 0.71 | — | — | |
| SCHEMBL206873 | 0.71 | — | — | |
| SCHEMBL25022124 | 0.69 | — | — | |
| SCHEMBL3909589 | 0.69 | — | — | |
| SCHEMBL8681375 | 0.69 | — | — | |
| SCHEMBL1071912 | 0.67 | — | — | |
| SCHEMBL283495 | 0.67 | — | — | |
| SCHEMBL5323681 | 0.65 | — | — | |
| SCHEMBL7804986 | 0.65 | — | — | |
| SCHEMBL28011840 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473464-B | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2022-08-23 | — | — | CN | claimed |
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | XIANG JASON SHAOYUN | 2010-02-04 | — | — | US | claimed |
| CN-101400653-A | 11-beta HSD1 inhibitors | WYETH CORP (US) | 2009-04-01 | — | — | CN | claimed |
| EP-1981848-A2 | 11-BETA HSD1 INHIBITORS | Wyeth (US) | 2008-10-22 | — | — | EP | claimed |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | WYETH (US) | 2007-09-20 | — | — | US | claimed |
| WO-2007092435-A2 | 11-BETA HSD1 INHIBITORS | WYETH (US) | 2007-08-16 | — | — | WO | claimed |
| US-5411955-A | Antiinflammatory agents, analgesics | LUITPOLD PHARMA GMBH (DE) | 1995-05-02 | — | — | US | claimed |
| US-4612143-A | Process for the preparation of fluoroformates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1986-09-16 | — | — | US | claimed |
| EP-0163888-A1 | Amidinohydrazones of derivatives of tetraline, chromone, thiachromone, and tetrahydroquinoline, process for their preparation, and their use in medicaments | BAYER AG (DE) | 1985-12-11 | — | — | EP | claimed |
| EP-0003901-A2 | 3-(Imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them | Pfizer Limited (GB) | 1979-09-05 | — | — | EP | claimed |
| CN-118344382-A | Quinoid poly condensed ring compound and electroluminescent device containing same | 华南理工大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344405-A | Organic electroluminescent material and device thereof | 北京夏禾科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344350-A | Organic electroluminescent material and device thereof | 北京夏禾科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118271367-A | Organic electroluminescent material and device thereof | 北京夏禾科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118284277-A | Electroluminescent device | 北京夏禾科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-7041859-B1 | Method for halogenating or radiohalogenating a chemical compound | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2006-05-09 | — | — | US | disclosed |
| US-4612143-A | Process for the preparation of fluoroformates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1986-09-16 | — | — | US | disclosed |
| EP-0163888-A1 | Amidinohydrazones of derivatives of tetraline, chromone, thiachromone, and tetrahydroquinoline, process for their preparation, and their use in medicaments | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-RE30633-E | DIURETICS | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1981-06-02 | — | — | US | disclosed |
| US-4122266-A | TO FORM LUBRICATING OIL ADDITIVES | CHEVRON RESEARCH COMPANY (US) | 1978-10-24 | — | — | US | disclosed |