SCHEMBL148100

SCHEMBL148100

CC(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
KMT2A Q03164 3/20 0.48
CTSK P43235 9/20 0.47
CTSS P25774 5/20 0.47
CYP2D6 P10635 1/20 0.46
GAA P10253 2/20 0.46
MEN1 O00255 1/20 0.46
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
CA12 O43570 1/20 0.43
CA14 Q9ULX7 1/20 0.43
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
GLS O94925 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17957327 1.00 CA1 (0.52) CA1CA2CA7KMT2ACTSK
SCHEMBL256594 1.00 CA1 (0.52) CA1CA2CA7KMT2ACTSK
SCHEMBL148099 1.00 CA1 (0.52) CA1CA2CA7KMT2ACTSK
Hydrochloric Acid SCHEMBL28175164 0.98 CA1 (0.50) CA1CA2CA7KMT2ACTSK
Hydrochloric Acid SCHEMBL28228115 0.98 CA1 (0.50) CA1CA2CA7KMT2ACTSK
Hydrochloric Acid SCHEMBL30428440 0.98 CA1 (0.50) CA1CA2CA7KMT2ACTSK
Cyclopentane SCHEMBL28225777 0.94 KMT2A (0.48) CA1CA2CA7KMT2ACTSK
SCHEMBL7057277 0.92 KMT2A (0.50) CA1CA2CA7KMT2ACTSK
SCHEMBL9980671 0.92 KMT2A (0.50) CA1CA2CA7KMT2ACTSK
Alanine SCHEMBL9180204 0.92 CA1 (0.46) CA1CA2CA7KMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2754 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125353-A1 METHOD OF PREPARATION OF ZAVEGEPANT, SYNTHESIS INTERMEDIATES OF ZAVEGEPANT AND METHODS OF PREPARATION THEREOF MOEHS IBERICA, S.L. (ES) 2025-06-19 WO claimed
CN-119039213-A Method for constructing tetra-substituted olefin by remote C (sp 3) -H bond biaryl 广西科学院 2024-11-29 CN claimed
CN-116478690-B Stable perovskite nanocrystalline based on novel ligand and preparation method thereof 天津大学 2024-05-28 CN claimed
CN-116478690-A Stable perovskite nanocrystalline based on novel ligand and preparation method thereof 天津大学 2023-07-25 CN claimed
CN-111315746-B Tryptophan hydroxylase inhibitors and pharmaceutical compositions comprising the same 光州科学技术院 2022-11-29 CN claimed
EP-3674303-B1 NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND PHARMACEUTICAL COMPOSITION INCLUDING SAME GWANGJU INST SCIENCE & TECH (KR) 2022-07-20 EP claimed
CN-113321773-B Chiral chromatographic packing of substituted polyacetylene grafted divinylbenzene microsphere and preparation method thereof 浙江理工大学 2022-07-12 CN claimed
CN-113321773-A Chiral chromatographic packing of substituted polyacetylene grafted divinylbenzene microspheres and preparation method thereof 浙江理工大学 2021-08-31 CN claimed
CN-111440173-B Preparation method of PI3K inhibitor 山东大学 2021-05-14 CN claimed
EP-2831073-B1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES RHIZEN PHARMACEUTICALS S A (CH) 2020-12-09 EP claimed
EP-1668005-A1 ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES Pharmacia & Upjohn Company LLC (US) 2006-06-14 EP claimed
US-20050267104-A1 E.g., ({[Acetyl({(5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran4-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}-methyl)amino]carbonyl}oxymethyl acetate; these compounds have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria PHARMACIA & UPJOHN COMPANY LLC 2005-12-01 US claimed
CN-1687076-A Compound of dual functional esterified prodrug of Cefetamet, and oral preparation ZHU XIAOMAO (CN) 2005-10-26 CN claimed
WO-2005028473-A1 ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY LLC (US) 2005-03-31 WO claimed
EP-0847994-B1 Process for the preparation of mixed anhydrides HOFFMANN LA ROCHE (CH) 2003-04-09 EP claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
EP-0204775-A4 AMINO ACID AND PEPTIDE INHIBITORS OF HUMAN LEUCOCYTIC ELASTASE. UNIV TROBE (AU) 1989-10-04 EP claimed
EP-0204775-A1 AMINO ACID AND PEPTIDE INHIBITORS OF HUMAN LEUCOCYTIC ELASTASE AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) 1986-12-17 EP claimed
WO-1986003746-A1 AMINO ACID AND PEPTIDE INHIBITORS OF HUMAN LEUCOCYTIC ELASTASE LA TROBE UNIVERSITY (AU) 1986-07-03 WO claimed