Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | HBB | P68871 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893307 | 0.87 | USP2 (0.54) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL13739384 | 0.86 | USP2 (0.45) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL8889980 | 0.86 | USP2 (0.53) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL8891807 | 0.85 | USP2 (0.52) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL13739319 | 0.84 | USP2 (0.49) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL8892466 | 0.83 | USP2 (0.54) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL8902682 | 0.83 | USP2 (0.52) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL13737764 | 0.83 | USP2 (0.48) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL13738242 | 0.81 | USP2 (0.52) | KDM4EUSP2TP53CYP3A4CASP1 | |
| SCHEMBL15732799 | 0.80 | KDM4E (0.46) | KDM4EUSP2TP53CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013043558-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2013-03-28 | — | — | WO | disclosed |