Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.69 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | TPH1 | P17752 | 3/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43862 | 1.00 | GRB2 (0.76) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| SCHEMBL43861 | 1.00 | GRB2 (0.76) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL4364332 | 0.98 | GRB2 (0.73) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL16289248 | 0.98 | GRB2 (0.73) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL29399075 | 0.98 | GRB2 (0.73) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| Dl-Phenylalanine SCHEMBL28313877 | 0.95 | SLC7A5 (0.71) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| SCHEMBL28901130 | 0.94 | GRB2 (0.68) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| SCHEMBL28901132 | 0.94 | GRB2 (0.68) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| SCHEMBL13205275 | 0.92 | GRB2 (0.66) | GRB2PTPN1SLC7A5PTGS1ALPI | |
| SCHEMBL21803821 | 0.91 | GRB2 (0.64) | GRB2PTPN1SLC7A5PTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151135-A1 | METHODS OF TREATING CANCER AND/OR CHEMOTHERAPY RELATED CONDITIONS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS | ENDEVICA BIO, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025123055-A1 | NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS AND ASSOCIATED METHODS FOR MODULATING WEIGHT GAIN | ENDEVICA BIO, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| EP-4444740-A2 | P53 PEPTIDOMIMETIC MACROCYCLES | Merck Sharp & Dohme LLC (US) | 2024-10-16 | — | — | EP | claimed |
| CN-116730969-A | Beta-lapachone-amino acid conjugate, and preparation method and application thereof | 中国药科大学 | 2023-09-12 | — | — | CN | claimed |
| WO-2023107353-A2 | P53 PEPTIDOMIMETIC MACROCYCLES | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | claimed |
| EP-4100064-A1 | TARGETED PLASMA PROTEIN DEGRADATION | Novartis AG (CH) | 2022-12-14 | — | — | EP | claimed |
| CN-115335081-A | Targeted plasma protein degradation | 诺华股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| US-11274126-B2 | pH-sensitive cyclic peptides | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-15 | — | — | US | claimed |
| WO-2021156792-A1 | TARGETED PLASMA PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2021-08-12 | — | — | WO | claimed |
| EP-3432908-A1 | pH-SENSITIVE PEPTIDES | Rhode Island Council on Postsecondary Education (US) | 2019-01-30 | — | — | EP | claimed |
| WO-2017165452-A1 | pH-SENSITIVE PEPTIDES | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) | 2017-09-28 | — | — | WO | claimed |
| CN-106986495-A | A kind of removable movable pot integrated sewage treating apparatus and its method of work | 徐州工程学院 | 2017-07-28 | — | — | CN | claimed |
| WO-2009100441-A2 | DEPOT FORMULATIONS | IMPAX LABORATORIES, INC. (US) | 2009-08-13 | — | — | WO | claimed |
| US-20260083834-A1 | CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY | TRANSFERT PLUS LP (CA) | 2026-03-26 | — | — | US | disclosed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250367300-A1 | Nanomaterial and Methods of Use Thereof | UNIVERSITY OF CONNECTICUT (US) | 2025-12-04 | — | — | US | disclosed |
| EP-1109831-A2 | CYCTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES | ALPHARMA AS (NO) | 2001-06-27 | — | — | EP | disclosed |
| EP-1109827-A2 | BIOACTIVE PEPTIDES | ALPHARMA AS (NO) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012542-A2 | CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES | ALPHARMA AS (NO) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012541-A2 | CYTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES | ALPHARMA AS (NO) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274126-B2 | pH-sensitive cyclic peptides | VIP, PHLPP1, PHLPP2 | GRB2 1995/4885PTPN1 1659/4885SLC7A5 227/4885 |
| US-20250367300-A1 | Nanomaterial and Methods of Use Thereof | EPCAM, CD47, JAK2 | GRB2 2365/4885PTPN1 26/4885SLC7A5 1405/4885 |
| US-20260083834-A1 | CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY | VSIG8, MICA, CD74 | GRB2 2704/4885PTPN1 1570/4885SLC7A5 1741/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | GRB2 2544/4885PTPN1 2490/4885SLC7A5 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.