Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817206 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1ALDH1A1PPARD | |
| SCHEMBL12914743 | 0.91 | LPAR3 (0.52) | LPAR3LPAR2LPAR1PPARDCA12 | |
| SCHEMBL1261244 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL8747080 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL8750565 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL11369751 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL9436997 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL3819079 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL28683465 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL1260687 | 0.88 | LPAR3 (0.67) | LPAR3LPAR2LPAR1P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404832-B2 | Short interfering ribonucleic acid (siRNA) for oral administration | NOVARTIS AG (CH) | 2013-03-26 | — | — | US | disclosed |