Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817279 | 1.00 | ELANE (0.45) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL14817249 | 0.92 | KMT2A (0.49) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730866 | 0.86 | ELANE (0.42) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730864 | 0.85 | POLB (0.44) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730868 | 0.84 | ELANE (0.40) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730865 | 0.84 | MAPT (0.45) | ELANEKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14817298 | 0.84 | KMT2A (0.44) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL14817295 | 0.81 | ELANE (0.41) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730781 | 0.80 | PRSS1 (0.39) | ELANEKMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL12730787 | 0.80 | NPC1 (0.38) | ELANEKMT2ASMN1; SMN2HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404316-B2 | Polymerizable liquid crystal compound and its polymer | JNC CORPORATION (JP) | 2013-03-26 | — | — | US | disclosed |