⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030394 | 1.00 | — | — | |
| SCHEMBL1503838 | 1.00 | — | — | |
| SCHEMBL1503889 | 1.00 | — | — | |
| SCHEMBL1988050 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1504074 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL21240457 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL14844672 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL21240455 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL16655313 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL14844671 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825316-A1 | FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-9951079-B2 | Fused tricyclic heterocyclic compounds as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170305923-A1 | FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-10-26 | — | — | US | disclosed |
| EP-3057957-A1 | CYCLOPENTYLBENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PSYCHOTIC AND COGNITIVE DISORDERS | Takeda Pharmaceutical Company Limited (JP) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055994-A1 | CYCLOPENTYLBENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PSYCHOTIC AND COGNITIVE DISORDERS | TAKEDA CAMBRIDGE LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |
| EP-1405852-B9 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2013-03-27 | — | — | EP | disclosed |