Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14803148 | 0.93 | ANO1 (0.41) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14803203 | 0.82 | ANO1 (0.42) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6927478 | 0.82 | ANO1 (0.53) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6926748 | 0.81 | ANO1 (0.54) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14818539 | 0.81 | ANO1 (0.52) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14803149 | 0.81 | ANO1 (0.47) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14803289 | 0.80 | ANO1 (0.44) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14803179 | 0.79 | MEN1 (0.47) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14818485 | 0.79 | ANO1 (0.65) | ANO1ANO2 | |
| SCHEMBL14818542 | 0.79 | MEN1 (0.50) | ANO1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | ANO1 114/4885MEN1 2958/4885KMT2A 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.