Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | CYCS | P99999 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670048 | 0.92 | STAT3 (0.51) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL7258061 | 0.87 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL10100940 | 0.87 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL30372046 | 0.87 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL27992764 | 0.86 | STAT3 (0.63) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL29823978 | 0.86 | STAT3 (0.62) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL3995625 | 0.85 | STAT3 (0.78) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL1863470 | 0.83 | STAT3 (0.59) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL7257316 | 0.81 | STAT3 (0.56) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL7257952 | 0.81 | STAT3 (0.56) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130074920-A1 | Photo-Switchable Fullerene-Based Materials as Interfacial Layers in Organic Photovoltaics | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-03-28 | — | — | US | disclosed |