Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 9/20 | 0.68 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361684 | 0.88 | AGPAT2 (0.56) | AGPAT2CDK9ALDH1A1APPLMNA | |
| SCHEMBL4361915 | 0.88 | AGPAT2 (0.85) | AGPAT2CDK9ALDH1A1LMNAMAPT | |
| SCHEMBL4371820 | 0.84 | AGPAT2 (0.76) | AGPAT2CDK9ALDH1A1LMNANPC1 | |
| SCHEMBL2622395 | 0.84 | APP (0.52) | AGPAT2CDK9ALDH1A1APPLMNA | |
| SCHEMBL4362048 | 0.83 | AGPAT2 (0.81) | AGPAT2CDK9ALDH1A1LMNAMAPT | |
| SCHEMBL2622396 | 0.83 | AGPAT2 (0.48) | AGPAT2CDK9ALDH1A1APPLMNA | |
| SCHEMBL29406206 | 0.81 | AGPAT2 (1.00) | AGPAT2CDK9ALDH1A1LMNANPC1 | |
| SCHEMBL13622457 | 0.81 | AGPAT2 (1.00) | AGPAT2CDK9ALDH1A1LMNANPC1 | |
| SCHEMBL4361700 | 0.81 | AGPAT2 (0.77) | AGPAT2CDK9ALDH1A1LMNAMAPT | |
| SCHEMBL4360664 | 0.81 | AGPAT2 (0.73) | AGPAT2CDK9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2572712-A2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-03-27 | — | — | EP | disclosed |