SCHEMBL14819787

SCHEMBL14819787

CCCOCCOCC(=O)NCCOCCOCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.59
NOD1 Q9Y239 10/20 0.43
SELP P16109 1/20 0.37
CCKAR P32238 1/20 0.37
CCKBR P32239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15002720 1.00 GLP1R (0.59) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL16867531 0.98 GLP1R (0.56) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL12673949 0.94 GLP1R (0.56) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL15002721 0.94 GLP1R (0.57) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL17131140 0.94 GLP1R (0.57) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL15358433 0.93 GLP1R (0.66) GLP1RNOD1CCKARCCKBR
SCHEMBL15267729 0.93 GLP1R (0.59) GLP1RNOD1CCKARCCKBR
SCHEMBL14819891 0.93 GLP1R (0.49) GLP1RNOD1SELP
SCHEMBL15002704 0.92 GLP1R (0.55) GLP1RNOD1SELPCCKARCCKBR
SCHEMBL17131127 0.92 GLP1R (0.54) GLP1RNOD1SELPCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160347812-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2016-12-01 US disclosed
US-9486505-B2 Glucagon analogues NOVO NORDISK A/S (DK) 2016-11-08 US disclosed
US-9486506-B2 Glucagon analogues NOVO NORDISK A/S (DK) 2016-11-08 US disclosed
US-20150374794-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK A/S (DK) 2015-12-31 US disclosed
US-20150182594-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2015-07-02 US disclosed
US-20130288958-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2013-10-31 US disclosed
US-8541368-B2 Glucagon analogues NOVO NORDISK A/S (DK) 2013-09-24 US disclosed
US-20130079278-A1 Novel Glucagon Analogues NOVO NORDISK A/S (DK) 2013-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374794-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 1398/4885SELP 655/4885
US-20150182594-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GCG, GCGR GLP1R 1/4885NOD1 1939/4885SELP 1311/4885
US-20130079278-A1 Novel Glucagon Analogues GLP1R, GCG, GCGR GLP1R 1/4885NOD1 1939/4885SELP 1311/4885
US-20130288958-A1 Novel Glucagon Analogues GLP1R, GCG, GCGR GLP1R 1/4885NOD1 1939/4885SELP 1311/4885
US-20160347812-A1 Novel Glucagon Analogues GLP1R, GCG, GCGR GLP1R 1/4885NOD1 1939/4885SELP 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.