Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14797227 | 0.90 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797414 | 0.84 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797383 | 0.84 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797243 | 0.83 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797156 | 0.83 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797054 | 0.81 | EIF4E (1.00) | EIF4E | |
| SCHEMBL17188919 | 0.81 | EIF4E (0.80) | EIF4E | |
| SCHEMBL14797219 | 0.80 | EIF4E (1.00) | EIF4E | |
| SCHEMBL14797375 | 0.80 | EIF4E (1.00) | EIF4E | |
| SCHEMBL28075994 | 0.80 | EIF4E (0.85) | EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758380-B1 | BENZOIC ACID DERIVATIVES AS EIF4E INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-10-21 | — | — | EP | disclosed |
| WO-2013041468-A1 | BENZOIC ACID DERIVATIVES AS EIF4E INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-28 | — | — | WO | disclosed |