⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822914 | 0.97 | CARM1 (0.54) | — | |
| SCHEMBL21386205 | 0.84 | HRH3 (0.52) | — | |
| SCHEMBL24081402 | 0.82 | HRH3 (0.56) | — | |
| SCHEMBL14824991 | 0.82 | HRH3 (0.56) | — | |
| SCHEMBL24081401 | 0.80 | HRH3 (0.61) | — | |
| SCHEMBL19966100 | 0.79 | CARM1 (0.41) | — | |
| SCHEMBL18941920 | 0.79 | ACE2 (0.39) | — | |
| SCHEMBL3341356 | 0.77 | CA12 (0.50) | — | |
| SCHEMBL19604995 | 0.77 | SLC2A1 (0.40) | — | |
| SCHEMBL21846921 | 0.77 | HSD17B10 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |
| EP-2884982-B1 | SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS | MERCK SHARP & DOHME (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2024360-B1 | SUBSTITUTED PYRAZOLOPYRIMIDINES | CEPHALON INC (US) | 2013-04-03 | — | — | EP | disclosed |