Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | PTAFR | P25105 | 2/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825796 | 0.89 | SETD7 (0.52) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL14825805 | 0.85 | PTAFR (0.49) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL14693497 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL3783252 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL3030543 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL8177110 | 0.77 | HRH3 (0.55) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL14825801 | 0.76 | HRH1 (0.49) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL14693488 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL14693597 | 0.76 | HRH1 (0.58) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL9718734 | 0.75 | HRH1 (0.55) | KDM4EALDH1A1HPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365553-B2 | Heterocyclic compound and H1 receptor antagonist | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365553-B2 | Heterocyclic compound and H1 receptor antagonist | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20130085127-A1 | HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST | ASKA PHARMACEUTICAL CO., LTD (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20130085127-A1 | HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST | ASKA PHARMACEUTICAL CO., LTD (JP) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085127-A1 | HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST | HRH2, HRH4, HRH1 | KDM4E 2670/4885ALDH1A1 2121/4885HPGD 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.