Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.66 |
| ▸ | PDE1A | P54750 | 2/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14827542 | 0.99 | PDE4A (0.67) | PDE4APDE1APDE1B | |
| SCHEMBL7521297 | 0.92 | PDE4A (0.79) | PDE4APDE1APDE1B | |
| SCHEMBL7512612 | 0.91 | PDE4A (0.80) | PDE4APDE1APDE1B | |
| SCHEMBL14827543 | 0.88 | PDE4A (0.85) | PDE4APDE1APDE1B | |
| SCHEMBL14827544 | 0.86 | PDE4A (0.88) | PDE4APDE1APDE1B | |
| SCHEMBL12198194 | 0.85 | PDE1A (0.74) | PDE4APDE1APDE1B | |
| SCHEMBL15869815 | 0.84 | PDE1A (0.84) | PDE4APDE1APDE1B | |
| SCHEMBL15869800 | 0.83 | PDE1A (0.84) | PDE4APDE1APDE1B | |
| SCHEMBL12198193 | 0.82 | PDE4A (0.85) | PDE4APDE1APDE1B | |
| SCHEMBL18380631 | 0.82 | PDE4A (0.85) | PDE4APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556185-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20130085123-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085123-A1 | ORGANIC COMPOUNDS | TPMT, TYMS, P2RX4 | PDE4A 701/4885PDE1A 4773/4885PDE1B 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.