Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 4/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829354 | 0.87 | HRH4 (0.39) | HRH4PIK3CDTRPV1KITAVPR1A | |
| SCHEMBL14829444 | 0.86 | MAP4K4 (0.47) | HRH4PIK3CDTRPV1SLC6A7KIT | |
| SCHEMBL14829443 | 0.86 | MAP4K4 (0.47) | HRH4PIK3CDTRPV1SLC6A7KIT | |
| SCHEMBL14828795 | 0.80 | HRH4 (0.38) | HRH4TRPV1 | |
| SCHEMBL14828773 | 0.79 | HRH4 (0.43) | HRH4 | |
| SCHEMBL14828755 | 0.77 | HRH4 (0.74) | HRH4 | |
| SCHEMBL14829442 | 0.77 | HRH4 (0.47) | HRH4 | |
| SCHEMBL14828834 | 0.76 | HRH4 (0.39) | HRH4 | |
| SCHEMBL14829324 | 0.76 | HRH4 (0.44) | HRH4 | |
| SCHEMBL14828974 | 0.76 | HRH4 (0.43) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760865-A2 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C Research Laboratories (KR) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013048214-A2 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C RESEARCH LABORATORIES (KR) | 2013-04-04 | — | — | WO | disclosed |