SCHEMBL14829936

SCHEMBL14829936

O=C(O)CCO.O=CC(O)COP(=O)(O)O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.49
PGK1 P00558 1/20 0.47
PGK2 P07205 1/20 0.47
PGD P52209 4/20 0.44
LPAR1 Q92633 4/20 0.35
LPAR6 P43657 1/20 0.35
LPAR4 Q99677 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
ENPP2 Q13822 1/20 0.35
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395698 0.85 MPI (0.63) MPIPGK1PGK2PGDLPAR1
SCHEMBL28125367 0.85 MPI (0.63) MPIPGK1PGK2PGDLPAR1
SCHEMBL10709491 0.85 MPI (0.63) MPIPGK1PGK2PGDLPAR1
SCHEMBL328992 0.85 MPI (0.63) MPIPGK1PGK2PGDLPAR1
SCHEMBL34088 0.85 MPI (0.63) MPIPGK1PGK2PGDLPAR1
Phosphoric Acid SCHEMBL6754811 0.83 MPI (0.61) MPIPGK1PGK2PGDLPAR1
Ammonia Solution, Strong SCHEMBL28280469 0.83 MPI (0.61) MPIPGK1PGK2PGDLPAR1
Phosphoric Acid SCHEMBL17103808 0.83 MPI (0.61) MPIPGK1PGK2PGDLPAR1
SCHEMBL10794963 0.82 AKR1B1 (0.56) MPIPGK1PGK2PGDLPAR1
SCHEMBL18341376 0.82 MPI (0.55) MPIPGK1PGK2PGDLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190161786-A1 METHODS FOR SELECTING ENZYMES HAVING PROTEASE ACTIVITY NOVOZYMES A/S (DK) 2019-05-30 US disclosed
EP-3440207-A1 METHODS FOR SELECTING ENZYMES HAVING PROTEASE ACTIVITY Novozymes A/S (DK) 2019-02-13 EP disclosed
US-20180355404-A1 METHODS FOR SELECTING ENZYMES HAVING LIPASE ACTIVITY NOVOZYMES A/S (DK) 2018-12-13 US disclosed
EP-2751261-B1 DEHYDROGENASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES INC (US) 2018-08-29 EP disclosed
US-20180073017-A1 METHODS FOR SELECTING ENZYMES HAVING ENHANCED ACTIVITY NOVOZYMES A/S (DK) 2018-03-15 US disclosed
EP-3280817-A2 METHODS FOR SELECTING ENZYMES HAVING ENHANCED ACTIVITY Novozymes A/S (DK) 2018-02-14 EP disclosed
EP-3280818-A2 METHODS FOR SELECTING ENZYMES HAVING LIPASE ACTIVITY Novozymes A/S (DK) 2018-02-14 EP disclosed
WO-2017177153-A1 METHODS FOR SELECTING ENZYMES HAVING PROTEASE ACTIVITY NOVOZYMES A/S (DK) 2017-10-12 WO disclosed
US-9404091-B2 Dehydrogenase variants and polynucleotides encoding same NOVOZYMES, INC. (US) 2016-08-02 US disclosed
US-20160017296-A1 Dehydrogenase Variants and Polynucleotides Encoding Same NOVOZYMES INC (US) 2016-01-21 US disclosed
US-9163220-B2 Dehydrogenase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2015-10-20 US disclosed
US-20140212938-A1 Dehydrogenase Variants and Polynucleotides Encoding Same NOVOZYMES A/S (DK) 2014-07-31 US disclosed
EP-2751261-A1 DEHYDROGENASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes, Inc. (US) 2014-07-09 EP disclosed
US-8728788-B1 Dehydrogenase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2014-05-20 US disclosed
WO-2013049073-A1 DEHYDROGENASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES, INC. (US) 2013-04-04 WO disclosed