Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830451 | 1.00 | KMT2A (0.51) | KMT2AMEN1NAAAMAPTALDH1A1 | |
| SCHEMBL18350198 | 0.93 | MEN1 (0.57) | KMT2AMEN1NAAA | |
| SCHEMBL15686649 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL3230862 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL5652692 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL3103625 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL10066970 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL14971389 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9841873 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4478966 | 0.88 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760820-A2 | SPHINGOSINE ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | Emory University (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013049280-A2 | SPHINGOSINE ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-04-04 | — | — | WO | disclosed |