Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14816228 | 1.00 | EPHX2 (0.39) | EPHX2SCN3ALIPGALOX5APFEN1 | |
| SCHEMBL14815998 | 0.91 | SCN3A (0.37) | SCN3ALIPGALOX5APFEN1GPR119 | |
| SCHEMBL15462531 | 0.91 | SCN3A (0.37) | SCN3ALIPGALOX5APFEN1GPR119 | |
| SCHEMBL14815884 | 0.91 | SCN3A (0.40) | SCN3ALIPGALOX5APFEN1GPR119 | |
| SCHEMBL15462411 | 0.90 | MEN1 (0.45) | EPHX2SCN3ALIPGALOX5APFEN1 | |
| SCHEMBL14815992 | 0.90 | MEN1 (0.45) | EPHX2SCN3ALIPGALOX5APFEN1 | |
| SCHEMBL14816013 | 0.89 | NPC1 (0.44) | SCN3AALOX5APFEN1MCHR1MEN1 | |
| SCHEMBL14816010 | 0.88 | NR1H2 (0.37) | SCN3ALIPGALOX5APFEN1GPR119 | |
| SCHEMBL14815434 | 0.86 | KDM4E (0.41) | SCN3AGPR119HSD11B1MEN1ALDH1A1 | |
| SCHEMBL14815581 | 0.86 | KDM4E (0.41) | SCN3AGPR119HSD11B1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049174-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-A]PYRAZINE SULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | WO | claimed |